Friday, July 27, 2018

Germs immune system air quality, Colorado?

Nice summer weather, cool down to 50s? last night I had to get up and put on more sheets.
Fan all night to bring in oxygen fresh air and probiotic natural microbes all over the house, clothes, skin, lungs,…
Trees pump out oxygen.
My few allergies mostly cured by nature but many suffer from allergies this time of year probably due to indoor mold in the air conditioners and toxic dump furniture and clothes.
I suddenly start to feel better after consuming 4 different brands of Yogurt with probiotic active cultures even though said yogurt contains pure cane sugar.

30 years ago walking downtown Market Street San Francisco I saw 2 bearded rolling stone homeless hippies sitting on a bench.
1 was shitting on the sidewalk.
The other looked at me and said "he is crazy"
Human feces contains huge amounts germs.
I was reading about the HIV aids epidemic and how some gays had thousands of sexual partners.
Obviously a huge path to spreading disease.
I sometimes walked thru Haight-Ashbury the little park on the west side where dozens of drug addicts including women and children would play.
Even the sidewalk seemed gooey and infected.
I started to use paper towels on every door I opened.

I often drove to Silicon Valley down Route 1 by the San Francisco sewage processing plant that stinks to the high heavens.
Also in Los Angeles I drove by the sewage processing plant that also stinks to the high heavens.
In both cases some poorer areas of the cities were downwind of stinking aerosolized feces.
In Los Angeles the poor areas are also downwind of the huge Port of Los Angeles diesel fumes.

I could see the poor general health of much of the population often due to infectious disease, lack of sun, and lack of exercise.
I walked by 1 house frequently and could see a huge cancer of green slime mold consuming it from the top down, oozing out of windows and under the rafters.
I could feel the pressure of molds in my sinuses.

My father nearly died from a super bug infection 1985 so I did a lot of study on hospital acquired infections and superbugs which was a big problem even back then.
UCLA figured out the right drug protocol to save him.
He was living downwind of central valley dairies which stink to the high heaven from airborne feces.
Cows injected with antibiotics and fed GMO glyphosate grains from Iowa etc.
Recipe for superbug disaster and the milk tastes terrible.
Antibiotic resistant germs in the air sloshing in additional pollutants in the toxic central valley air.

Such observations led me to decide to leave SF and polluted high tax California in general.
Less polluted areas are infested with marijuana grown in chemicals guarded by illegals with guns in houses and meth labs that sometimes explode.
Frequent murders, missing, dead bodies discovered, most never reported.

I had always been suspicious of much of California because of the general uncleanliness of many areas and the poor health of the people.
Constant fog and humidity increases germ and mold growth.
And the extreme liberal politics lifestyle whiskey alcohol of the Irish Catholic population Suspicious.
So I moved to Tahoe which was much better on some counts and had zero income tax and often conservative.
High altitude, bright sun, heat, cold and low population decrease germ and mold growth in the air and surfaces indoor, etc.
Lots of outdoor exercise and the whole outdoor beauty culture.

Home air filtration and conditioning may help.
Along with water filtration.
But a complete geographical change would be needed to get away from all of the attacks to your health and survival.

I see some studies are finally getting some data on what I observed decades ago:
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The thick fog rolling over San Francisco's Golden Gate bridge is synonymous with the Bay Area.

But more than an emblem for the coastal city, the fog may also represent a massive highway for genes that create dangerous, antibiotic- resistant "super bugs,"

The rise of super-bacteria through the overprescription and misuse of antibiotics is hard enough to control as it is, but now, it looks like they may be emerging out of the air.

The alarming spread of infections from super gonorrhea and Staphylococcus aureus shows just how bad the antibiotic- resistant bacteria problem has become.

In January, the World Health Organization found that 500,000 people across 22 countries had antibiotic-resistant infections that were nearly untreatable.

The reason these superbugs are so dangerous is because they carry certain antibiotic resistance genes (ARGs) that protect them from most drugs

Usually, ARGs spread when one lucky superbug survives after a dosage of antibiotic drugs kills most of its comrades,
allowing that superbug to multiply,
creating its own colony of minions that share its superior genetic material.

But the team behind the new study found that in these ARGs can spread a different way:

They can become airborne, traveling from bacteria to bacteria around the world — creating new forms of superbugs.

The team was surprised to find that cities with thick smog, like Beijing didn't actually have the highest amount of airborne ARGs.

"ARGs could travel through air to remote regions or other places where antibiotics on the other hand are less used,"

"Common bacteria could become resistant to antibiotics when uptaking these ARGs."

Airborne ARGs make Yao and his team nervous is because they represent bacteria's second, more difficult-to-manage method of accumulating genes.

Unlike animals that have to wait to give birth to pass their genetic material on to the next generation, bacteria can inject each other with genetic material, including ARGs.

The effects are permanent because the genes get encoded in the DNA of the recipient bacteria.

This process, called horizontal transfer, is what makes airborne resistance such a threat.

Air currents that circulate in urban environments swirl around millions of people every day, greatly increasing the possibility that a typical resistant bacteria might meet an antibiotic-resistant one.

The cities in the world with the most diversity of ARGs in the air

Globetrotting ARGs

The jarring observation raised two questions for Yao.

What cities throughout the world are ARG tourism hotspots,

and how do they get into the air in the first place?

To investigate this, the team sampled the level of bacteria in the air from 19 cities including San Francisco, Beijing, and Paris using a particularly ingenious method.

They randomly selected cars from each city and took samples of particles that had accumulated on the inside of the AC filters, which have been shown to faithfully represent particles in outdoor pollutants

By scraping the filters themselves, the team had plenty of samples to screen for their ARGs.

Their screening revealed 30 different types of ARGs that make bacteria resistant to seven types of antibiotics.

Beijing, China
and Brisbane, Australia
topped the list as the cities with the most diversity of ARGs in the air, but the types of ARGs in the air varied greatly from city to city.

For instance, Melbourne's air contained high levels of airborne genes that conferred resistance to drugs like penicillin and
low levels of genes that conferred resistance to ciproflaxin, an antibiotic used to treat typhoid.

This analysis aside, one city topped the list with the highest concentrations of ARGs in their air: San Francisco.

Although the city had less overall pollution in the air than particulate-dense cities like Beijing, Yao was surprised to discover that

the Bay Area had more airborne ARGs than Paris, Beijing, and Singapore and more than 100 times more ARGs than the relatively small city of Bandung, Indonesia.

"For some cities with good air quality, we have detected higher abundances of ARGs, even including ARGs that are tailored to resist the most powerful antibiotics,"

Where did they come from?

Yao suggests that these genes originate in places like wastewater treatment plants, hospitals or animal feeding operations.

Wastewater, specifically, is often treated with antibiotics that, if unsuccessful in killing all bacteria, could lead the survivors to evolve a host of resistance genes.

Previous researchhas also shown wastewater is likely to be aerosolized — meaning that the particles present in the water can become airborne.

Whatever is driving the spread of antibiotic resistance, it's time to double down on containing it,

"So far a lot of research effort to tackle this problem has been around hospitals and reducing clinical prescribing, but we now know that the environment

is likely to play a part in how resistance to antibiotics can evolve and spread,"

"We all need to think more holistically about environmental management of waste,
including how we treat our waste water."

Even if the genes of those bacteria living in wastewater don't eventually become airborne globetrotters floating in cities around the world

keeping our sewage under control might be a good place to start.

do the citizens of San Francisco a favor and stop flushing antibiotics down the toilet.

Superbugs are in the air:
People are breathing in antibiotic resistant genes in major cities around the world, reveal scientists

Researchers found antibiotic resistant genes floating in the air of 19 global cities

They say the genes could be breathed in and spread to new bacteria

Antibiotic resistance is expected to kill millions of people in the coming decades

It causes infections which used to be treatable to become immune to antibiotics

As well as soot and exhaust fumes city air could be filling our lungs with antibiotic resistant genes, a study has found.

Some two million people in the US are thought to become infected with drug-resistant bacteria every year, and they could be inhaling them from the air.

The genes which cause bacteria to become immune to medication – antibiotic resistant genes (ARGs) –
are able to move between different bacteria
and also from bacteria into the environment

research by the American Chemical Society revealed scientists have found the airborne genes in farms and parks in America.

This confirms drug resistance could be spread through the air

It suggests bacteria could acquire their ability to survive antibiotic treatment – and become superbugs – from the air we breathe.

Scientists say air quality monitoring must also focus on the risk of breathing in antibiotic resistant genes, as well as lung-damaging soot and fuel

Antibiotic resistance is a spreading global problem which means once easily- treatable infections could become superbugs that cannot be cured.

Figures estimate these superbugs will kill 10 million people a year by 2050.

Experts predict a 'post-antibiotic' world

The World Health Organisation has warned the world could enter a 'post-antibiotic' era in which medicines no longer work as bacteria become tougher and tougher.

The new research, led by Peking University, examined the levels of antibiotic resistant genes in the air of 19 cities around the world.

San Francisco had the highest levels of the airborne ARGs,
whereas the air in Beijing contained genes with resistance to a wider range of antibiotics.

These genes are a risk to health because they may be absorbed by bacteria which were not previously able to survive antibiotics,
meaning more and more infections could become impossible to treat.

Cities worldwide have penicillin resistant genes in the air

In all cities, genes were most commonly resistant to penicillin and similar drugs,
as well as a class of medicines called quinolones which are used to treat urinary tract infections, gonnorhoea, and pneumonia.

Other cities the researchers tested included Paris, Johannesburg, Zurich, Warsaw, Hong Kong, Brisbane and Melbourne.

The air of six of the cities contained genes resistant to a last-resort treatment for highly infectious hospital superbug.
Staph MRSA, which is already immune to most antibiotics.

threat of airborne transmission'

Remote regions even without using antibiotics could be exposed to the second hand ARGs,
which are initially being developed in other regions but transported elsewhere.

threat of airborne transmission of ARGs and the need of redefining our current air quality standards in terms with public health in an urban city.'

WHAT IS ANTIBIOTIC RESISTANCE?

Antibiotics have been doled out unnecessarily by doctors for decades,
fueling once harmless bacteria to become superbugs.

The World Health Organization (WHO) has previously warned if nothing is done the world is heading for a 'post-antibiotic' era.

It claimed common infections, such as chlamydia, will become killers without immediate solutions to the growing crisis.

Bacteria can become drug resistant when people take incorrect doses of antibiotics or if they are given out unnecessarily.

Chief medical officer Dame Sally Davies claimed in 2016 that the threat of antibiotic resistance is as severe as terrorism.

Figures estimate that superbugs will kill 10 million people each year by 2050,
with patients succumbing to once harmless bugs.

Around 700,000 people already die yearly due to drug-resistant infections including tuberculosis (TB), HIV and malaria across the world.

Concerns have repeatedly been raised that medicine will be taken back to the 'dark ages' if antibiotics are rendered ineffective in the coming years.

In addition to existing drugs becoming less effective, there have only been one or two new antibiotics developed in the last 30 years.

In September, the WHO warned antibiotics are 'running out'
as a report found a 'serious lack' of new drugs in the development pipeline.

People are breathing in antibiotic resistant genes in major cities around the world

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